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Tolerability and pharmacokinetics of intravitreal sirolimus

Mudumba S., Bezwada P., Takanaga H., Hosoi K., Tsuboi T., Ueda K., Kawazu K., Ali Y., Naor J.

  • 2012
  • Journal of Ocular Pharmacology and Therapeutics
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  • Therapeutic Area

    Back of the eye (BOTE)

  • Technology

    Pharmacology

  • Categories

    Preclinical development

  • Affiliations

    Pharmaceutical and Preclinical Development Department, Santen Incorporated, 2100 Powell Street, Emeryville, CA 94608, United States; Santen Pharmaceutical Co, Ltd., Ikoma-shi, Nara, Japan

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Pyridylmethylthio derivatives as VEGF inhibitors. Part 1

Tajima H., Honda T., Kawashima K., Sasabuchi Y., Yamamoto M., Ban M., Okamoto K., Inoue K., Inaba T., Takeno Y., Aono H.

  • 2010
  • Bioorganic and Medicinal Chemistry Letters
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Valosin-containing protein modulator KUS121 protects retinal neurons in a rat model of anterior ischemic optic neuropathy

Kikkawa C., Ikeda H.O., Hata M., Iwai S., Tsujikawa A.

  • 2025
  • Sci. Rep.
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Rapid and efficient generation of mature retinal organoids derived from human pluripotent stem cells via optimized pharmacological modulation of Sonic hedgehog, activin A, and retinoic acid signal transduction

Matsushita T.; Onishi A.; Matsuyama T.; Masuda T.; Ogino Y.; Kageyama M.; Takahashi M.; Uchiumi F.

  • 2024
  • PLoS ONE
View publication
View all Back of the eye (BOTE) publications

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Document number: NP-No product-EMEA-0110
Date of preparation: February 2022

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