Mapracorat, a selective glucocorticoid receptor agonist, upregulates RelB, an anti-inflammatory nuclear factor-kappaB protein, in human ocular cells
Spinelli S.L., Xi X., McMillan D.H., Woeller C.F., Richardson M.E., Cavet M.E., Zhang J.-Z., Feldon S.E., Phipps R.P.
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Therapeutic Area
Front of the eye (FOTE)
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Categories
Clinical development
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Affiliations
Department of Pathology and Laboratory Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY, United States; Department of Ophthalmology, University of Rochester School of Medicine and Dentistry, Rochester, NY, United States; University of Rochester School of Medicine and Dentistry, Rochester, NY, United States; Flaum Eye Institute, University of Rochester School of Medicine and Dentistry, Rochester, NY, United States; Global Pharmaceutical R and D, Bausch and Lomb, Inc., Rochester, NY, United States; Department of Pathology, University of Vermont, Burlington, VT, United States; Preclinical Development, Santen Inc., Emeryville, CA, United States