Paroxetine markedly increases plasma concentrations of ophthalmic timolol; cyp2d6 inhibitors may increase the risk of cardiovascular adverse effects of 0.5% timolol eye drops

Mäenpää J., Volotinen-Maja M., Kautiainen H., Neuvonen M., Niemi M., Neuvonen P.J., Backman J.T.

2014
Drug Metabolism and Disposition

Therapeutic Area

Glaucoma
Categories

Clinical development

Affiliations

Santen Oy, Tampere, Finland; Medcare Oy, Äänekoski, Finland; Department of Clinical Pharmacology, University of Helsinki, Helsinki University Central Hospital, P.O. Box 705, HUS, Helsinki, FI- 00029, Finland

Related Publications

Felodipine re-positioned as a neuroprotectant via improved optic nerve head blood circulation in retinal ischemic rabbits and ocular hypertensive rats

Taniguchi T, Akaishi T, Hata T, Yamashita R, Esaki Y, Morofuji R, Okabe K, Fuwa M, Yamamoto Y, Guo L, Choi S, Luong V, Ota T, Sharif NA, Cordeiro MF, Kageyama M.

A Study of 24-h Efficacy and Safety of Sepetaprost vs. Latanoprost in Patients with Primary Open-Angle Glaucoma or Ocular Hypertension

Konstas A.G.; Garhöfer G.; Lübke Y.; Voykov B.; Ropo A.

Valproic Acid Application to Modify Post Surgical Fibrosis in a Model of Minimally Invasive Bleb Surgery

Lo P.F.; Gunawan M.; Yap Z.L.; Leong C.; Kwek F.; Varadarajan J.; Wang X.; Kageyama M.; Wong T.T.

View all Glaucoma publications