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Consensus Recommendation for Mouse Models of Ocular Hypertension to Study Aqueous Humor Outflow and Its Mechanisms

McDowell C.M., Kizhatil K., Elliott M.H., Overby D.R., van Batenburg-Sherwood J., Cameron Millar J., Kuehn M.H., Zode G., Acott T.S., Anderson M.G., Bhattacharya S.K., Bertrand J.A., Borras T., Bovenkamp D.E., Cheng L., Danias J., De Ieso M.L., Du Y., Faralli J.A., Fuchshofer R., Ganapathy P.S., Gong H., Herberg S., Hernandez H., Humphries P., John S.W.M., Kaufman P.L., Keller K.E., Kelley M.J., Kelly R.A., Krizaj D., Kumar A., Leonard B.C., Lieberman R.L., Liton P., Liu Y., Liu K.C., Lopez N.N., Mao W., Mavlyutov T., McDonnell F., McLellan G.J., Mzyk P., Nartey A., Pasquale L.R., Patel G.C., Pattabiraman P.P., Peters D.M., Raghunathan V., Rao P.V., Rayana N., Raychaudhuri U., Reina-Torres E., Ren R., Rhee D., Chowdhury U.R., Samples J.R., Griffen Samples E., Sharif N., Schuman J.S., Sheffield V.C., Stevenson C.H., Soundararajan A., Subramanian P., Sugali C.K., Sun Y., Toris C.B., Torrejon K.Y., Vahabikashi A., Vranka J.A., Wang T., Willoughby C.E., Xin C., Yun H., Zhang H.F., Fautsch M.P., Tamm E.R., Clark A.F., Ross Ethier C., Daniel Stamer W.


  • 2022
  • Investigative Ophthalmology and Visual Science
View publication
  • Therapeutic Area

    Glaucoma

  • Categories

    Preclinical development

  • Affiliations

    Department of Ophthalmology and Visual Sciences, University of Wisconsin–Madison, Madison, WI, United States; The Jackson Laboratory, Bar Harbor, ME, United States; University of Oklahoma Health Sciences Center, Oklahoma City, OK, United States; Department of Bioengineering, Imperial College London, United Kingdom; Department of Pharmacology & Neuroscience, North Texas Eye Research Institute, University of North Texas Health Science Center, Fort Worth, TX, United States; Department of Ophthalmology and Visual Sciences, Institute for Vision Research, The University of Iowa, Center for the Prevention and Treatment of Visual Loss, Veterans Affairs Medical Center, Iowa City, IA, United States; Ophthalmology and Biochemistry and Molecular Biology, Casey Eye Institute, Oregon Health & Science University, Portland, OR, United States; Department of Molecular Physiology and Biophysics, Department of Ophthalmology and Visual Sciences, The University of Iowa, Center for the Prevention and Treatment of Visual Loss, Veterans Affairs Medical Center, Iowa City, IA, United States; Bascom Palmer Eye Institute, University of Miami, Miami, FL, United States; Department of Bioengineering, Imperial College London, London, United Kingdom; University of North Carolina at Chapel Hill, Chapel Hill, NC, United States; Brightfocus Foundation, Clarksburg, MD, United States; Department of Ophthalmology and Visual Sciences, University of Iowa, Iowa City, IA, United States; SUNY Downstate Health Sciences University, Brooklyn, NY, United States; Department of Ophthalmology, Duke Eye Center, Duke University, Durham, NC, United States; Department of Ophthalmology, University of PittsburghPA, United States; Department of Pathology and Laboratory Medicine, University of Wisconsin–Madison, Madison, WI, United States; Institute of Human Anatomy and Embryology, University of Regensburg, Regensburg, Germany; Department of Ophthalmology and Visual Sciences, SUNY Upstate Medical University, Syracuse, NY, United States; Department of Ophthalmology, Boston University School of Medicine, Boston, MA, United States; University of Houston–Victoria, Victoria, TX, United States; Smurfit Institute of Genetics, Trinity College Dublin, Dublin, Ireland; Department of Ophthalmology, Columbia University, New York, NY, United States; Casey Eye Institute, Oregon Health & Science University, Portland, OR, United States; Department of Ophthalmology, Department of Integrative Biosciences, Oregon Health & Science University, Portland, OR, United States; Ocular Genetics Unit, Smurfit Institute of Genetics, Trinity College Dublin, Dublin, Ireland; Department of Ophthalmology, University of Utah School of Medicine, Salt Lake City, UT, United States; Department of Surgical and Radiological Sciences, University of California, Davis, Davis, CA, United States; Department of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, GA, United States; Department of Ophthalmology, Department of Pathology, Duke University, Durham, NC, United States; Department of Cellular Biology and Anatomy, James & Jean Culver Vision Discovery Institute, Augusta University, Augusta, GA, United States; Duke Eye Center, Duke Health, Durham, NC, United States; Department of Neurobiology, University of Utah, Salt Lake City, UT, United States; Department of Ophthalmology, Indiana University School of Medicine, Indianapolis, IN, United States; Department of Surgical Sciences and Department of Ophthalmology and Visual Sciences, University of Wisconsin–Madison, Madison, WI, United States; College of Optometry, University of Houston, Houston, TX, United States; Department of Ophthalmology, Icahn School of Medicine at Mount Sinai, New York, NY, United States; Ophthalmology Research, Regeneron Pharmaceuticals, TarreytownNY, United States; Department of Ophthalmology, Duke University School of Medicine, Durham, NC, United States; Department of Neurobiology, University of California, Irvine, Irvine, CA, United States; Case Western Reserve University School of Medicine, Cleveland, OH, United States; Department of Ophthalmology, Mayo Clinic, Rochester, MN, United States; Washington State University, Floyd Elson College of Medicine, Spokane, WA, United States; Western Glaucoma Foundation, Sisters, OR, United States; Santen Inc., Emeryville, CA, United States; Department of Ophthalmology, Department of Physiology and Neuroscience, NYU Grossman School of Medicine, NYU Langone Health, New York University, New York, NY, United States; Departments of Biomedical Engineering and Electrical and Computer Engineering, New York University Tandon School of Engineering, Brooklyn, NY, United States; Center for Neural Science, College of Arts and Science, New York University, New York, NY, United States; Department of Pediatrics, Department of Ophthalmology and Visual Sciences, University of Iowa Carver College of Medicine, Iowa City, IA, United States; Veterans Affairs Palo Alto Health Care System, Stanford University, Palo Alto, CA, United States; Department of Ophthalmology and Visual Sciences, University of Nebraska Medical Center, Omaha, NE, United States; Department of Ophthalmology and Vision Sciences, The Ohio State University, Columbus, OH, United States; Glauconix Biosciences, Albany, NY, United States; Cell and Developmental Biology Department, Northwestern University, Chicago, IL, United States; Department of Ophthalmology, Casey Eye Institute, Oregon Health & Science University, Portland, OR, United States; Genomic Medicine, Biomedical Sciences Research Institute, Ulster University, Coleraine, United Kingdom; Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing, China; Department of Ophthalmology, University of Pittsburgh, Pittsburgh, PA, United States; Biomedical Engineering Department, Northwestern University, Evanston, IL, United States; University of Regensburg, Regensburg, Germany; Department of Pharmacology and Neuroscience, North Texas Eye Research Institute, University of North Texas Health Science Center, Fort Worth, TX, United States; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology, Emory University School of Medicine, Emory University, Atlanta, GA, United States; Duke Ophthalmology, Duke University, Durham, NC, United States; Department of Ophthalmology, Mayo Clinic, Rochester, MN, United States; University of Regensburg, Regensburg, Germany; Department of Pharmacology and Neuroscience, North Texas Eye Research Institute, University of North Texas Health Science Center, Fort Worth, TX, United States; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology, Emory University School of Medicine, Emory University, Atlanta, GA, United States; Duke Ophthalmology, Duke University, Durham, NC, United States

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Document number: NP-No product-EMEA-0110
Date of preparation: February 2022