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KUS121, a VCP modulator, attenuates ischemic retinal cell death via suppressing endoplasmic reticulum stress

Hata M., Ikeda H.O., Kikkawa C., Iwai S., Muraoka Y., Hasegawa T., Kakizuka A., Yoshimura N.

  • 2017
  • Scientific Reports
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  • Therapeutic Area

    Back of the eye (BOTE)

  • Categories

    Preclinical development

  • Affiliations

    Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan; Neuroprotective Treatment Project for Ocular Diseases, Institute for Advancement of Clinical and Translational Science, Kyoto University Hospital, Kyoto, Japan; Pharmacology Group, Non-clinical Research, Global RandD, Santen Pharmaceutical Co., Ltd, Nara, Japan; Laboratory of Functional Biology, Kyoto Univ. Graduate School of Biostudies AndSolution Oriented Research for Science and Technology, Kyoto, Japan

Related Publications

Efficacy and Safety of Low-Concentration Atropine in Slowing Myopia Progression in Children in Japan: The Randomized, Double-Blind Phase II/III ORANGE Study

Ohno-Matsui K., Igarashi-Yokoi T., Migita Y., Yamakawa Y, on behalf of the ORANGE study investigators

  • 2025
  • Ophthalmology Science
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Awareness of Myopia Associated Complications and Perspectives on Myopia Management Among Parents of Children with Myopia in France and the UK

Hafizi R., Deferne N., Paudel N., Angerer A., Hsieh H.-T.

  • 2025
  • Patient Related Outcome Measures
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Cutamesine (SA4503) Protects Retinal Ganglion Cells in an Ocular Hypertension Model of Glaucoma Determined Using Detection of Apoptosing Retinal Cells Technology and RBPMS Cell Marker

Sharif N.A., Takashi O., Taniguchi T., Sasaoka M., Guo L., Choi S., Luong V., Cordeiro M.F.

  • 2025
  • J Ocul Pharmacol Ther
View publication
View all Back of the eye (BOTE) publications

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Document number: NP-No product-EMEA-0110
Date of preparation: February 2022

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