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Lessons Learned From Multi-regional Trials With Signals of Treatment Effect Heterogeneity

Li G., Quan H., Lan G., Ouyang S.P., Chen F., Robieson W., Wang W., Binkowitz B., Yuan S.S., Tanaka Y., Chen J., Matsuoka N., Zhang L., Yang S., Gallo P.

  • 2020
  • Therapeutic Innovation and Regulatory Science
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  • Categories

    Clinical development

  • Affiliations

    Janssen R&D US, 920 US Highway 202 S, Raritan, NJ 08869, United States; Sanofi, Bridgewater, NJ, United States; SPO Consulting LLC, Kendall Park, NJ, United States; AbbVie Inc, North Chicago, IL, United States; Merck Research Laboratories, Kendall Park, NJ, United States; Shionogi Inc, Florham Park, NJ, United States; Santen, Inc., Emeryville, CA, United States; Pfizer, Japan; National Heart, Lung, and Blood Institute, Bethesda, MD, United States; Novartis Pharmaceuticals, East Hanover, NJ, United States

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Document number: NP-No product-EMEA-0110
Date of preparation: February 2022