MALDI imaging mass spectrometry revealed atropine distribution in the ocular tissues and its transit from anterior to posterior regions in the whole-eye of rabbit after topical administration

Affiliations

Nara Research and Development Center, Santen Pharmaceutical Co., Ltd., Ikoma-shi, Nara, Japan; Department of Cellular and Molecular Anatomy, Hamamatsu University, School of Medicine, Hamamatsu, Shizuoka, Japan; International Mass Imaging Center, Hamamatsu University, School of Medicine, Hamamatsu, Shizuoka, Japan; Laboratory of Fish Biology, Department of Environmental Biology, College of Bioscience and Biotechnology, Chubu University, Kasugai, Aichi, Japan; Department of Systems Molecular Anatomy, Institute for Medical Photonics Research, Preeminent Medical Photonics Education and Research Center, Hamamatsu, Shizuoka, Japan; Department of Anatomy, University of Hong Kong, Pokfulam, China