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Mapracorat, a selective glucocorticoid receptor agonist, upregulates RelB, an anti-inflammatory nuclear factor-kappaB protein, in human ocular cells

Spinelli S.L., Xi X., McMillan D.H., Woeller C.F., Richardson M.E., Cavet M.E., Zhang J.-Z., Feldon S.E., Phipps R.P.


  • 2014
  • Experimental Eye Research
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  • Therapeutic Area

    Front of the eye (FOTE)

  • Categories

    Clinical development

  • Affiliations

    Department of Pathology and Laboratory Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY, United States; Department of Ophthalmology, University of Rochester School of Medicine and Dentistry, Rochester, NY, United States; University of Rochester School of Medicine and Dentistry, Rochester, NY, United States; Flaum Eye Institute, University of Rochester School of Medicine and Dentistry, Rochester, NY, United States; Global Pharmaceutical R and D, Bausch and Lomb, Inc., Rochester, NY, United States; Department of Pathology, University of Vermont, Burlington, VT, United States; Preclinical Development, Santen Inc., Emeryville, CA, United States

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Document number: NP-No product-EMEA-0110
Date of preparation: February 2022