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P2X7 receptor activation may be involved in neuronal loss in the retinal ganglion cell layer after acute elevation of intraocular pressure in rats

Sugiyama T., Lee S.Y., Horie T., Oku H., Takai S., Tanioka H., Kuriki Y., Kojima S., Ikeda T.

  • 2013
  • Molecular Vision
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  • Therapeutic Area

    Glaucoma

  • Categories

    Preclinical development

  • Affiliations

    Department of Ophthalmology, Osaka Medical College, Takatsuki, Osaka, Japan; Nune Eye Hospital, Seoul, South Korea; Department of Pharmacology, Osaka Medical College, Osaka, Japan; Nara Research and Development Center, Santen Pharmaceutical Co. Ltd, Takayama-cho, Ikoma-shi, Nara, Japan

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Long-term safety and efficacy of sepetaprost, with or without timolol, in patients with open-angle glaucoma or ocular hypertension: results from the randomised, phase 3 ANGEL-J2 study

Inatani M., Tone Y., Ikeda T., Angeles R.

  • 2026
  • Jpn J Ophthalmol
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Efficacy and safety of sepetaprost in patients with primary open-angle glaucoma or ocular hypertension: results from the randomised, phase 3 ANGEL-J1 study

Inatani M., Kanamori A., Inai M., Ikeda T., Angeles R.

  • 2026
  • Jpn J Ophthalmol
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Clinical outcomes of Preserflo MicroShunt implant procedure in open‑angle glaucoma patients – a 1000 eyes case-series; including subanalysis of combined cataract-glaucoma surgery and standalone surgery in pseudophakic eyes

Klabe, K.; Werth, J.P.; Kaymak, H. ; Fricke, A.

  • 2026
  • Graefe's Archive for Clinical and Experimental Ophthalmology
View publication
View all Glaucoma publications

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Document number: NP-No product-EMEA-0110
Date of preparation: February 2022

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