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The Role of EP3 Agonism in Intraocular Pressure-Lowering by Sepetaprost, a Novel Dual Agonist of FP and EP3 Receptors, in Monkeys

Maki K., Kimura E., Yamamoto Y., Fuwa M., Toris C.B., Fan S., Shimazaki A., Kato M.


  • 2025
  • Journal of Ocular Pharmacology and Therapeutics
View publication
  • Therapeutic Area

    Glaucoma

  • Categories

    Preclinical development

  • Affiliations

    Pharmaceutics and Pharmacology Department, Santen Pharmaceutical Co., Ltd., Ikoma, Nara, Japan. Department of Ophthalmology and Visual Sciences, Stanley M. Truhlsen Eye Institute, University of Nebraska Medical Center, Omaha, Nebraska, USA. Department of Ophthalmology and Visual Sciences, Havener Eye Institute, The Ohio State University College of Medicine and Wexner Medical Center, Columbus, Ohio, USA.

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Document number: NP-No product-EMEA-0110
Date of preparation: February 2022