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Valosin-containing protein modulator KUS121 protects retinal neurons in a rat model of anterior ischemic optic neuropathy

Kikkawa C., Ikeda H.O., Hata M., Iwai S., Tsujikawa A.

  • 2025
  • Sci. Rep.
View publication

  • Therapeutic Area

    Back of the eye (BOTE)

  • Categories

    Preclinical development

  • Affiliations

    Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Sakyo-ku, Kyoto, 606-8507, Japan; Product Development Division, Santen Pharmaceutical Co., Ltd, Nara, Japan; Department of Ophthalmology, Osaka Medical and Pharmaceutical University, Osaka, Japan

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Functional significance of commonly regulated genes in mechanically and chemically induced retinal ganglion cell death in rat eyes

Kageyama M, Ohashi K, Ota T.

  • 2025
  • Sci. Rep.
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Rapid and efficient generation of mature retinal organoids derived from human pluripotent stem cells via optimized pharmacological modulation of Sonic hedgehog, activin A, and retinoic acid signal transduction

Matsushita T.; Onishi A.; Matsuyama T.; Masuda T.; Ogino Y.; Kageyama M.; Takahashi M.; Uchiumi F.

  • 2024
  • PLoS ONE
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Rotenone-Induced Optic Nerve Damage and Retinal Ganglion Cell Loss in Rats

Yamamoto Y.; Taniguchi T.; Shimazaki A.

  • 2024
  • Biomolecules
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View all Back of the eye (BOTE) publications

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Document number: NP-No product-EMEA-0110
Date of preparation: February 2022

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