Novel use of a chemically modified siRNA for robust and sustainable in vivo gene silencing in the retina

Taniguchi T., Endo K.-I., Tanioka H., Sasaoka M., Tashiro K., Kinoshita S., Kageyama M.

2020
Scientific Reports

Therapeutic Area

Back of the eye (BOTE)
Technology

Drug Delivery
Categories

Preclinical development

Affiliations

Research and Development Division, Santen Pharmaceutical Co., Ltd., 8916-16 Takayama-cho, Ikoma-shi, Nara, 630-0101, Japan; Global Alliances and External Research, Santen Pharmaceutical Co., Ltd, Nara, Japan; Department of Genomic Medical Sciences, Kyoto Prefectural University of Medicine, Kyoto, Japan; Department of Frontier Medical Science and Technology for Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan

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